Abstract
Current cancer treatments include surgical intervention, radiation, and chemotherapy medications. Nanoparticles have a variety of advantages as medication delivery systems. Nanoparticles (NPs) are newly discovered methods for delivering medicines to tumour cells with little drug leakage into healthy cells. To enhance biodistribution and increase circulation duration in the bloodstream, nanoparticles have been developed with optimum size and surface properties. Here, I look at the many types and features of nanoparticles. Examples of commercially available nanocarrier-based medicines include: Therapeutic nanoparticles, the function of metal nanoparticles in cancer diagnosis and therapy, are important ideas in nanoparticle medication delivery for cancer.
Highlights
With more than 10 million new cases diagnosed each year, cancer remains one of the world's most deadly diseases [1]
Molecular targeted therapy has emerged as one solution to the lack of specificity in traditional chemotherapeutic drugs [3].Resistance development in cancer cells, on the other hand, can avoid the cytotoxicity of both traditional chemotherapeutics and novel molecular targeted treatments [4]
Active techniques do this by combining chemotherapeutic-loaded nanocarriers with compounds that attach to overexpressed antigens or receptors on target cells
Summary
With more than 10 million new cases diagnosed each year, cancer remains one of the world's most deadly diseases [1]. Conventional chemotherapeutic drugs lack focused action and are dispersed non- throughout the body, affecting both cancerous and non-cancerous cells, limiting the amount delivered to tumor cells and resulting in unsatisfactory treatment due to high toxicity. Nanoparticles can boost intracellular drug concentration in cancer cells while minimizing toxicity in normal cells by using both passive and active targeting techniques [5, 6]. Passive targeting exploits tumor biology's distinctive traits, such as increased permeability and retention (EPR), which permits nanocarriers to concentrate in a tumor [2]. Active techniques do this by combining chemotherapeutic-loaded nanocarriers with compounds that attach to overexpressed antigens or receptors on target cells.
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