Abstract
Calotropis gigantea, known locally as Aak or Madar in Hindi, is recognized as milkweeds due to their latex production. These Calotropis species are acknowledged as common weeds in specific regions and have been integral to traditional Indian medicinal practices. This review delves into the systematic position, plant introduction, morphological examination, phytochemistry, and economic significance of Calotropis gigantea within the Apocynaceae family and Asclepiadoideae subfamily. Flourishing in diverse soils and natural environments, this plant necessitates no cultivation practices. The review explores various pharmacological activities, including antioxidant, anti-malarial, antimicrobial, cytotoxic, and antipyretic effects. Keywords: Calotropis gigantea Linn, pharmacological investigations.
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