Abstract
Seizure can be the first symptom of diabetic hyperglycemia and cause transient abnormalities in neuroimaging studies. Herein, we report the case of a 72-year-old woman with a one-month history of intermittent clonic movement of the left upper limb and neck. Laboratory testing revealed non-ketotic hyperglycemia. Electroencephalography showed asymmetrical background with delta activity over right frontal-temporal lobe. Brain magnetic resonance imaging revealed leptomeningeal and cortical enhancement in the right parieto-occipital area with T2 hypointensity in the corresponding subcortical area, a finding which has been rarely reported. She was treated successfully with oral hypoglycemic agents and short-term use of valproic acid. Follow-up brain magnetic resonance imaging three months later showed total recovery of the signal changes with residual mild cortical atrophy in the same region. For patients with diabetic hyperglycemia and prolonged seizures which results in abnormalities of brain imaging consistent with leptomeningeal and cortical enhancement, valproic acid may be beneficial in abolishing the seizures. (J Intern Med Taiwan 2011; 22: 438-443)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
