Abstract
Aortic stenosis (AS) is characterized by gradual thickening, fibrosis, and calcification leading to reduced opening of aortic valve leaflets. Aortic valve narrowing increases the afterload on left ventricle (LV), which consequently leads to hypertrophy and myocardial fibrosis which over a period of time leads to diastolic dysfunction. LV diastolic dysfunction is an independent predictor of heart failure rehospitalization and mortality in post-aortic valve replacement patients. Chronic pressure overload leads to development of systolic dysfunction due to afterload mismatch. Patients with severe symptomatic AS and depressed LV function without significant myocardial scarring will derive maximum benefit after percutaneous valve replacement and thus show immediate improvement after reduction of LV afterload. We report two such cases which had good LV function recovery immediately after transcatheter aortic valve replacement (TAVR).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
