Abstract

BackgroundTo compare the perioperative outcomes of transperitoneal laparoscopic (TLA), retroperitoneal laparoscopic (RLA), and robot-assisted transperitoneal laparoscopic (RATLA) adrenalectomy for adrenal tumors in our center.MethodsBetween April 2012 and February 2018, 241 minimally invasive adrenalectomies were performed. Cases were categorized based on the minimally invasive adrenalectomy technique. Demographic characteristics, perioperative information and pathological data were retrospectively collected and analyzed.ResultsThis study included 37 TLA, 117 RLA, and 87 RATLA procedures. Any two groups had comparable age, ASA score, Charlson Comorbidity Index, and preoperative hemoglobin. The tumor size for RLA patients was 2.7 ± 1.1 cm, which was significantly smaller compared to patients who underwent TLA/RATLA (p = 0.000/0.000). Operative time was similar in any two groups, while estimated blood loss was lower for RATLA group (75.6 ± 95.6 ml) compared with the TLA group (131.1 ± 204.5 ml) (p = 0.041). Conversion to an open procedure occurred in only one (2.7%) patient in the TLA group for significant adhesion and hemorrhage. There were no significant differences between groups in terms of transfusion rate and complication rate. Length of stay was shorter for the RATLA group versus the TLA/RLA group (p = 0.000/0.029). In all groups, adrenocortical adenoma and pheochromocytoma were the most frequent histotypes.ConclusionsMinimally invasive adrenalectomy is associated with expected excellent outcomes. In our study, the RATLA approach appears to provide the benefits of decreased estimated blood loss and length of stay. Robotic adrenalectomy appears to be a safe and effective alternative to conventional laparoscopic adrenalectomy.

Highlights

  • To compare the perioperative outcomes of transperitoneal laparoscopic (TLA), retroperitoneal laparoscopic (RLA), and robot-assisted transperitoneal laparoscopic (RATLA) adrenalectomy for adrenal tumors in our center

  • The RATLA approach appears to provide the benefits of decreased estimated blood loss and length of stay

  • Body mass index (BMI) was high in RLA group compared with the TLA group (p = 0.034)

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Summary

Introduction

To compare the perioperative outcomes of transperitoneal laparoscopic (TLA), retroperitoneal laparoscopic (RLA), and robot-assisted transperitoneal laparoscopic (RATLA) adrenalectomy for adrenal tumors in our center. About 10% of adrenal tumors are functional, and less than 5% are malignant. Laparoscopic adrenalectomy was first described in 1992 [2] At present it has routinely replaced the open procedure as the standard treatment for adrenal tumors, with the advantages such as less hemorrhage, shorter hospital stay, and minimally invasive incision [3,4,5]. Conventional laparoscopic adrenalectomy is generally performed by a transperitoneal laparoscopic (TLA) or retroperitoneal laparoscopic (RLA) approach. TLA is suitable for all sizes of tumors because of the large operating space, while RLA is a more direct approach to the adrenal gland, eliminating the dissection of adjacent structures. Laparoscopy is recognized as associated with a steep and prolonged learning curve for the nonarticulated instruments and inefficient force transmission

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