Abstract
IntroductionSplenosis is a post-traumatic autotrasplantation and proliferation of splenic tissue in ectopic sites. These implants may mimic malignancy in healthy patients or peritoneal metastases in cancer patients. When a previous history of splenic injury is known, the finding of soft tissue nodules in many thoracic and abdominal locations might raise the suspicion of the benign condition of splenosis, in order to avoid unnecessary surgery or chemotherapy.Case presentationA 56-year-old man with history of persistent hematuria from bladder cancer was referred to our Institution for suspected peritoneal carcinosis. For staging purposes he underwent abdominal computed tomography and ultrasound. The integration of patient's history and imaging results led to the diagnosis of peritoneal splenosis. The patient therefore underwent regular Trans Urethral Resection of Bladder for the known malignancy; while no treatment was necessary for splenosis. Two years follow-up was negative for metastases.ConclusionSplenosis is a benign condition after traumatic splenectomy which should be taken into account in the differential diagnosis with peritoneal seeding of malignancy because its appearance may resemble malignancy.
Highlights
R Conclusion: Splenosis is a benign condition after traumatic splenectomy which should be taken into account in the differential diagnosis with peritoneal seeding of malignancy because its appearance may resemble malignancy
Cases Journal 2009, 2:9294 http://www.casesjournal.com/content/2/1/9294 abovementioned locations might raise the suspicion of ence of peritoneal solid splenic-like masses on the sites splenosis in order to avoid unnecessary surgery or chemo- indicated by CT (Figure 2)
This report describes the case of a bladder cancer patient and the patient underwent usual TURV as treatment for with peritoneal splenosis mimicking metastases
Summary
Splenosis is a post-traumatic autotrasplantation and proliferation of splenic tissue in ectopic sites. It has been demonstrated that splenic Since these implants may mimic malignancy or peritoneal implants can survive and grow when transplanted to metastases, in cancer patients with previous history of ectopic sites, such as the splenic fossa, any site of the peri- splenic injury, the finding of soft tissue nodules in the (page number not for citation purposes). A 56-year-old white man native from Italy, was admitted to our Institution for a diagnosis of bladder cancer and a previous CT scan suggesting peritoneal carcinosis His history started about 4 months in advance for the occurrence of hematuria. His previous personal history was unremarkable, other than a car accident about 20 years in advance, which requested a long hospital staying and a splenectomy At our hospital he underwent a Trans-Urethral Resection of Bladder (TURB) which led to the diagnosis of spinocellular carcinoma of the bladder. The patient underwent a second computed tomography ment for splenosis
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