Abstract
This reply is a supplementary addition to our previous article entitled “Comparison of a Powdered, Acidified Liquid, and Non-Acidified Liquid Human Milk Fortifier on Clinical Outcomes in Premature Infants” as published in Nutrients in July 2016. It provides a response to a comment made by Dr. Fernando Moya to this original article, so the purpose of this is to compare and contrast various perspectives between researchers conducting nutrition research in the preterm infant population. It specifically focuses on human milk fortification and subsequent outcomes.
Highlights
Nutrients 2016, 8, 822 anticipated that infants received remaining nutrition from parenteral nutrition, which in turn would allow for initial closer management of acid-base balance
We cannot attribute our finding of lower carbon dioxide levels to preterm infants having poor metabolic adaptations in early life, as infants in our study receiving the P-HMF and NAL-HMF achieved full enteral feedings at similar days of life and experienced normal levels [1]
Our results clearly demonstrate that the median carbon dioxide level in our AL-HMF group remained below this reference range [1,2]
Summary
Nutrients 2016, 8, 822 anticipated that infants received remaining nutrition from parenteral nutrition, which in turn would allow for initial closer management of acid-base balance. The purpose of our wider inclusion criteria was to assess outcomes for a larger demographic population of low birth weight infants who require essential human milk fortification. Infants in the study by Moya et al were reported to be born at younger gestational ages and lower birth weights compared to those in our study [1,2].
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