Abstract
THE injection of androgens into the baby cockerel has proved to be of considerable value for the assay of male hormones—Frank and Klempner (1937–38), Emmens (1939a)—and for a study of male endocrine physiology, Breneman (1938a). Similar studies of the pullet are more incomplete and the problems less well understood. There is also some confusion regarding the relative responsiveness of male and female chicks to male hormone treatment. Burrows, Byerly, and Evans (1936) reported that the pullet is superior to the cockerel as a test animal, but Darby (1938) was unable to detect any difference in response between the two. Frank and Klempner, and Emmens are agreed that the cockerel gives a more marked reaction to male hormone treatment, but the latter suggests that the pullet is more satisfactory for assay purposes because the comb response is less variable. Two problems seem to be clearly indicated: first, what .
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