Responding to the Hitch in Fighting Candida Albicans Through Nanomedicine

Abstract

Candida albicans, as an opportunistic pathogen has been closely associated with both mucosal and deep tissue life-threatening infections in patients being immuno compromised or hospitalized for some grave underlying ailment. Antifungal therapy so far has not been much successful to reduce mortality and morbidity associated with candidiasis. Furthermore the complete eradication of fungal infection requires long-term treatment that may continue for a month, making patients more vulnerable to adverse effects. The emergence of Candida albicans resistant strains against commonly prescribed antifungals is also a major area of concern demandingimmediate consideration. Researchers are continuously investigating newer approaches to counter the deficiencies in conventional treatment strategies. One of these approaches involves the use of nanotechnology to overcome challenges associated with anti fungal therapy. This review focuses on various means that have been employed to effectively counter puzzles supplementary to Candida albicans by use of nano medicines.