Abstract
Background: Recently the resistance to activated protein C(APC-resistance) was identified to be the most common risk factor for deep vein thrombosis in the Caucasian population. Reports on a high frequency of APC-resistance in children and newborns with venous or arterial thrombembolism(Nowak-Gottl, Br J Hamatol 1996;92:992-8) and a high prevalence of thrombi within the large mesenteric artery branches in patients autopsied because of NEC (Ballance, J Pediatr 1990;117:S6-13), raising the question if APC-resistance is a risk factor for the development of neonatal necrotizing enterocolitis.
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