Medicina clinica | VOL. 158
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Residual lesions on chest-Xray after SARS-CoV-2 pneumonia: Identification of risk factors.

Publication Date May 13, 2022

Abstract

COVID-19 pneumonia is the most frequent clinical manifestation of this disease, and its long-term sequelae and possible progression to pulmonary fibrosis are still unknown. The aim of this study is a mid-term review of the sequelae on plain chest radiography (CXR) in patients with a previous diagnosis of COVID-19 pneumonia. Retrospective review of patients with a diagnosis of COVID-19 pneumonia, assessing the persistence of residual lesions in the control CXR and analysing their possible relationship with epidemiological factors, risk factors, treatments received and initial radiological patterns. A total of 143 patients (52 women and 91 men) were analysed. Mean age was 64 years. Radiological complete resolution (CR) was observed in 104 (73%) and partial resolution (PR) in 39 (27%). Of the risk factors only age was significantly related to persistence of residual lesions (OR 1.06 CI 95% (1.02,1.10). In relation to treatments, significant differences were found with tocilizumab and glucocorticoids, where treated patients had a higher risk of residual lesions (OR 2.44 (1.03,5.80) and 3.05(1.43,6.51) respectively. In the analysis of radiological patterns, significant differences were observed in patients with peripheral condensations in the acute course and a pattern of early radiological worsening. A clinical-radiological dissociation was evident: 83% of patients with residual lesions had no respiratory symptoms. COVID19 pneumonias may have a slower radiological resolution in older patients with certain initial radiological pa...

Concepts

Diagnosis Of COVID-19 Pneumonia COVID-19 Pneumonia Residual Lesions Development Of Pulmonary Fibrosis Clinical-radiological Dissociation Plain Chest Radiography Peripheral Condensations Identification Of Risk Factors Diagnosis Of Pneumonia Acute Course

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