Abstract

The upward trend of patients opting for elective breast augmentation, as well as the large number of patients benefiting from alloplastic breast reconstruction, require further studies on the safety profile of these techniques. Without any doubt, the incidence of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) has drawn attention to the possible unknown complications characteristic of these procedures, creating the context of further studies devoted to this issue. The present research examines the capsular contracture rate on a group of 253 patients between 2015 and 2019, also proposing a scoring system based on the integration of the main diagnostic criteria related to the capsular contracture. The results of the literature review indicate that a lower incidence of capsular contracture could be achieved by using the newest techniques in the field involving the application of chemical substances on the surface of the latest generation of silicone breast implants.

Highlights

  • The upward trend of patients opting for elective breast augmentation, as well as the large number of patients benefiting from alloplastic breast reconstruction, require further studies on the safety profile of these techniques

  • Without a doubt the understanding of the mechanisms involved in the physiopathological processes related to the occurence of the capsular contracture is extremely important, given the fact that the accelerated fibrosis of the capsule seems to be determined by the structure and the chemical materials used by the manufacturers

  • Recent data from the literature show that this type of surface can be associated with the appearance of BIAALCL [8], a factor that have led to the introduction of the micro- or nanotextured surface concept [9], which has the advantage of decreasing the capsular contracture rate by inhibiting the foreign body-type immune response [10], while reducing the risk of BIA-ALCL

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Summary

Experimental part Materials and methods

The research was conducted based on 253 patients that have undergone breast augmentation surgery between 2007 and 2013 for both aeshtetic and reconstruction purpuses. The plastic surgeons diagnosed these patients with capsular contracture, each of the patients being asked to rate their pain on a scale of 1 to 10. In order to determine the severity of the condition, the physician has rated the other 2 symptoms (breast firmness and deformity) using the same scale. Based on the data gathered during the consults, an evaluation matrix was developed in order to calculate a score that expresses the severity of the capsular contracture based on the 3 symptoms as evaluation criteria (PFD score) (table 1). The proposed scoring system is based on multiplying each of the values assigned to the patients’ symptoms during the surgical consult. The capsular contracture severity was determined using the American Society of Plastic Surgeons grading system [27] in relation with the proposed PFD score (table 2). In order to have a complete overview related to the patients’ status, the research has gathered data related to the breast augmentation procedure, as well as demographic data and the complete medical history

Results and discussions
Conclusions
Centralizing information using the proposed PFD score
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