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Research on U-Net medical image segmentation

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Abstract
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With the rapid development of deep learning technology and medical technology, neural networks are widely used in the field of medical image segmentation. Among them, U-Net neural network has gradually become a research hotspot in the field of image segmentation because of its good segmentation performance. It provides doctors with a consistent method of quantifying lesions and is widely used in the field of medical image semantic segmentation. This article studies the U-Net network, learns theoretically from the U-Net network model and its basic principles, and then conducts experiments on three typical medical images of liver medical images, fundus blood vessel images, and lung nodule images to explain various types of medical images. The characteristics of the image and the difficulty of segmentation, and the performance of the U-Net network in the relevant image segmentation is verified. Finally, the problems existing in U-Net network are discussed, and the future development is prospected.

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  • Research Article
  • Cite Count Icon 34
  • 10.1155/2019/6134942
Medical Image Segmentation Algorithm Based on Feedback Mechanism CNN
  • Aug 1, 2019
  • Contrast Media & Molecular Imaging
  • Feng-Ping An + 1 more

With the development of computer vision and image segmentation technology, medical image segmentation and recognition technology has become an important part of computer-aided diagnosis. The traditional image segmentation method relies on artificial means to extract and select information such as edges, colors, and textures in the image. It not only consumes considerable energy resources and people's time but also requires certain expertise to obtain useful feature information, which no longer meets the practical application requirements of medical image segmentation and recognition. As an efficient image segmentation method, convolutional neural networks (CNNs) have been widely promoted and applied in the field of medical image segmentation. However, CNNs that rely on simple feedforward methods have not met the actual needs of the rapid development of the medical field. Thus, this paper is inspired by the feedback mechanism of the human visual cortex, and an effective feedback mechanism calculation model and operation framework is proposed, and the feedback optimization problem is presented. A new feedback convolutional neural network algorithm based on neuron screening and neuron visual information recovery is constructed. So, a medical image segmentation algorithm based on a feedback mechanism convolutional neural network is proposed. The basic idea is as follows: The model for obtaining an initial region with the segmented medical image classifies the pixel block samples in the segmented image. Then, the initial results are optimized by threshold segmentation and morphological methods to obtain accurate medical image segmentation results. Experiments show that the proposed segmentation method has not only high segmentation accuracy but also extremely high adaptive segmentation ability for various medical images. The research in this paper provides a new perspective for medical image segmentation research. It is a new attempt to explore more advanced intelligent medical image segmentation methods. It also provides technical approaches and methods for further development and improvement of adaptive medical image segmentation technology.

  • Conference Article
  • Cite Count Icon 2
  • 10.1117/12.2671339
A medical image segmentation algorithm based on spatial and channel attention mechanisms and data augmentation
  • Apr 29, 2023
  • Yu Li + 2 more

With the development and progress of medical imaging technology, the resolution of medical images has been increasing, and a variety of high-definition imaging modalities such as CT, PET-CT and MRI have emerged. U-Net network has the advantages of simple network topology and small training set data requirement; thus, the field of medical image segmentation uses it extensively. However, U-Net also has some problems, such as edge loss of segmentation results, long training time and single application scenario. For the medical image segmentation problem, this paper proposes a method that combines channel attention and spatial attention and uses an improved join strategy to join the network structure. To address the problem of insufficient data volume of medical images, this paper performs a data augmentation operation on the dataset with elastic deformation. In addition, we use a local-global training strategy to further improve the performance of training on medical images. When compared to the original U-Net, the Dice coefficient and IOU metrics are significantly better when utilizing the method suggested in this work. After extensive experiments, the strategy proposed in this study can achieve good outcomes when facing medical image segmentation problems and has great potential.

  • Research Article
  • Cite Count Icon 6
  • 10.14257/ijsip.2015.8.7.21
Medical and Natural Image Segmentation Algorithm using M-F based Optimization Model and Modified Fuzzy Clustering: A Novel Approach
  • Jul 31, 2015
  • International Journal of Signal Processing, Image Processing and Pattern Recognition
  • Bingquan Huo + 2 more

In this paper, we propose and present a novel algorithm for medical image segmentation (MIS). By analyzing the current state-of-the-art related algorithms, we introduce the multi-band active contour model based limit function to make the multilayer segmentation available. With the development of image segmentation technology, the development of medical image segmentation technology also got very big, because there is no find common, accepted effect ideal is suitable for medical image segmentation method, almost existing each kind of segmentation method has application in the field of medical image segmentation. Furtherly, with the optimized aims of being robust to the noise and avoiding the bad effluence on the result, we adopt the kernel method and new initialization curve. This model suffers from low noise robustness, and model algorithm is difficult to achieve. Integrated segmentation technology refers to two or more technology is used, combined with their own advantages, so they can on the accuracy or efficiency to achieve better performance than when using a single. A new penalty term is introduced to improve numerical stability and the step length is increased to improve efficiency. As far as the robustness and effectiveness are concerned, our method is better than the existing medical image segmentation algorithms. Experimental analysis verifies the success of our method.

  • Conference Article
  • Cite Count Icon 24
  • 10.1109/iccrd.2010.155
An Improved Method of Segmentation Using Fuzzy-Neuro Logic
  • Jan 1, 2010
  • S Sathish Kumar + 3 more

Image segmentation is an important process to extract information from complex medical images. Segmentation has wide application in medical field. The main objective of image segmentation is to partition an image into mutually exclusive and exhausted regions such that each region of interest is spatially contiguous and the pixels within the region are homogeneous with respect to a predefined criterion. Widely used homogeneity criteria include values of intensity, texture, color, range, surface normal and surface curvatures. During the past, many researchers in the field of medical imaging and soft computing have made significant survey in the field of image segmentation. This paper aims to develop an improved method of segmentation using Fuzzy- Neuro logic to detect various tissues like white matter, gray matter; cerebral spinal fluid and tumor for a given magnetic resonance image data set. Generally magnetic resonance images always contain a significant amount of noise caused by operator performance, equipment, and the environment, which can lead to serious inaccuracies. So segmentation of such medical images is a challenging problem in the field of image analysis. Several diagnostics are based on proper segmentation of the digitized image. Segmentation of medical images is needed for applications involving estimation of the boundary of an object, classification of tissue abnormalities, shape analysis, contour detection. In particular Fuzzy-Neuro logic segmentation algorithm is used to provide satisfactory results compared to K-means, Fuzzy C-Means, Neural Network and Fuzzy logic.

  • Research Article
  • 10.2478/candc-2025-0004
Insights into U-NET models with special focus on ultrasound and MRI medical image segmentation
  • Mar 1, 2025
  • Control and Cybernetics
  • V B Shereena + 1 more

The advent of deep learning enabled the extraction of complex feature representations from medical imaging data, which was considered impossible to be achieved with standard computer learning. The applications of deep learning in the field of medical image analysis a ord significant results. A key feature of deep learning techniques is their ability to automatically learn task-specific feature representations and extract relevant features without human intervention. Various deep learning models, including CNN, AlexNet, ResNet, DenseNet and U-Net were developed for medical image analysis. Among these models, U-Net is a popular model, used for medical image segmentation. The present article provides a comprehensive review of the deep learning segmentation models, which use U-Net and its variants, applied in the domain of medical image segmentation, specifically tailored to medical imaging modalities, such as ultrasound and MRI, along with respective pros and cons in the field of image segmentation. The analysis reveals that the performance of di erent U-Net variants varies significantly based on imaging modality and segmentation complexity.

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  • Supplementary Content
  • Cite Count Icon 248
  • 10.1155/2022/9580991
Deep Neural Networks for Medical Image Segmentation.
  • Mar 10, 2022
  • Journal of Healthcare Engineering
  • Priyanka Malhotra + 4 more

Image segmentation is a branch of digital image processing which has numerous applications in the field of analysis of images, augmented reality, machine vision, and many more. The field of medical image analysis is growing and the segmentation of the organs, diseases, or abnormalities in medical images has become demanding. The segmentation of medical images helps in checking the growth of disease like tumour, controlling the dosage of medicine, and dosage of exposure to radiations. Medical image segmentation is really a challenging task due to the various artefacts present in the images. Recently, deep neural models have shown application in various image segmentation tasks. This significant growth is due to the achievements and high performance of the deep learning strategies. This work presents a review of the literature in the field of medical image segmentation employing deep convolutional neural networks. The paper examines the various widely used medical image datasets, the different metrics used for evaluating the segmentation tasks, and performances of different CNN based networks. In comparison to the existing review and survey papers, the present work also discusses the various challenges in the field of segmentation of medical images and different state-of-the-art solutions available in the literature.

  • Research Article
  • Cite Count Icon 31
  • 10.1007/s11042-021-10515-w
Medical image segmentation algorithm based on multilayer boundary perception-self attention deep learning model
  • Feb 1, 2021
  • Multimedia Tools and Applications
  • Feng-Ping An + 1 more

Traditional medical image segmentation methods have problems such as low segmentation accuracy and low adaptive ability. Therefore, many scholars have proposed a medical image segmentation method based on deep learning, which has achieved good results in the field of medical image segmentation. However, this type of method has the following problems in the application process: (1) Medical image segmentation target boundary positioning problem. Constrained by factors such as medical image contrast, heterogeneity, and boundary resolution, existing convolution models still cannot accurately locate boundaries. (2) Deep adaptability of deep learning network structure to medical images. Because medical images have more distinct and different feature information than natural images, the current deep learning-based medical segmentation methods have not fully considered this feature. In view of this, this paper proposes a multi-level boundary-aware RUNet segmentation model. The network structure consists of a U-Net-based segmentation network and a multi-level boundary detection network. It can solve the problem of boundary positioning. At the same time, in order to solve the problem of poor adaptability of deep learning network structures to medical images, this paper proposes to introduce a new interactive self-attention module into deep learning models. It can make the feature map get global information, and realize the effective extraction of medical image feature information. It solves the problem of weak matching between the deep learning network structure and medical images. Based on the above ideas, this paper proposes an image segmentation algorithm based on a multi-layer boundary perception-self-attention mechanism deep learning model. This method and other mainstream segmentation algorithms are used to perform experiments on related medical databases. The results show that the proposed method not only improves the segmentation effect significantly compared with traditional machine learning methods, but also improves it to a certain extent compared with other deep learning methods.

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  • Research Article
  • Cite Count Icon 18
  • 10.32604/cmes.2023.025499
Application of U-Net and Optimized Clustering in Medical Image Segmentation: A Review
  • Jan 1, 2023
  • Computer Modeling in Engineering & Sciences
  • Jiaqi Shao + 5 more

As a mainstream research direction in the field of image segmentation, medical image segmentation plays a key role in the quantification of lesions, three-dimensional reconstruction, region of interest extraction and so on. Compared with natural images, medical images have a variety of modes. Besides, the emphasis of information which is conveyed by images of different modes is quite different. Because it is time-consuming and inefficient to manually segment medical images only by professional and experienced doctors. Therefore, large quantities of automated medical image segmentation methods have been developed. However, until now, researchers have not developed a universal method for all types of medical image segmentation. This paper reviews the literature on segmentation techniques that have produced major breakthroughs in recent years. Among the large quantities of medical image segmentation methods, this paper mainly discusses two categories of medical image segmentation methods. One is the improved strategies based on traditional clustering method. The other is the research progress of the improved image segmentation network structure model based on U-Net. The power of technology proves that the performance of the deep learning-based method is significantly better than that of the traditional method. This paper discussed both advantages and disadvantages of different algorithms and detailed how these methods can be used for the segmentation of lesions or other organs and tissues, as well as possible technical trends for future work.

  • Research Article
  • Cite Count Icon 9
  • 10.1088/1742-6596/2209/1/012020
Spine Image Segmentation Based on U-Net and Atrous spatial pyramid pooling
  • Feb 1, 2022
  • Journal of Physics: Conference Series
  • Zhen Yang + 4 more

In the past ten years, deep learning has achieved remarkable results in the area of natural image segmentation, and has gradually turned to the field of medical image segmentation. The precise segmentation of spine images can be used for early screening of spondylopathy, which is convenient for early detection and treatment of patients. Aiming at the segmentation of the spine image by the U-Net network, which structure will lead to large model calculation, network overfitting, image size, noise information and other issues. This paper introduces a new method based on spatial pyramid pooling module ASpp on U-Net network and applies the proposed network structure to the segmentation of the spine image. The model is first enhanced by the Spp module and Densenet data; secondly, the U-Net encoding and decoding structure is adopted, and the deep separable convolution is used. This method greatly reduces the complexity and computation of the model, and uses a rectangular convolution kernel to increase the computation of the model in a small amount. Based on the volume, the receptive field of the convolution operation is expanded; finally, in order to effectively enhance the segmentation area of the image, the SE-Net attention mechanism module is added to the lateral connection. The method proposed in this paper conducts ablation experiments on a public dataset of spine images and compares it with the U-Net network. The method proposed IOU in this paper can reach 72%, and the F1-score can reach 0.92. The comparison of the experimental results of spine medical image datasets shows that the method proposed in this paper can effectively improve the accuracy and accuracy of spine image segmentation.

  • Conference Article
  • Cite Count Icon 17
  • 10.1109/isdea.2014.155
On Medical Image Segmentation Based on Wavelet Transform
  • Jun 1, 2014
  • Xu Gongwen + 3 more

The Image segmentation is the focus in the image processing technology all the time. Medical image segmentation is an important application in the field of image segmentation. Wavelet transform is proposed to segment medical image. Firstly the gray level histogram of the medical image was processed using multiscale wavelet transform. Then the gray threshold was gradually emerged by the performance from large scale factor to small scale factor. At last the difference of the effect between traditional method and wavelet transform method were compared. The experimental results showed that the last method surpasses the traditional one in image segmentation and the results has been demonstrated to have validity and practicability. Image segmentation can achieve the anatomical structures and other interesting information of a medical image automatically or semi-automatically, which is helpful on the medical diagnosis.

  • Research Article
  • 10.1109/jbhi.2026.3663638
RGShuffleNet: An Efficient Design for Medical Image Segmentation on Portable Devices.
  • Jan 1, 2026
  • IEEE journal of biomedical and health informatics
  • Zemin Cai + 3 more

Medical image segmentation plays a crucial role in intelligent medical image processing systems, serving as the foundation for effective medical image analysis, particularly in assisting diagnosis and surgical planning. Over the past few years, UNet has achieved tremendous success in the field of image segmentation, with several UNet-based extension models widely applied in medical image segmentation tasks. However, the application of these models is limited to scenarios where large medical equipment can be deployed, such as hospitals. The significant computational costs associated with these segmentation models pose significant challenges when deploying them on portable devices with limited hardware resources. This hinders the realization of rapid and efficient image segmentation in Homelab. In this paper, we present a lightweight model, RGShuffleNet, specifically designed for resource-constrained mobile devices for medical image segmentation. To reduce parameters and computational complexity, we first propose Reshaped Group Convolution, a novel convolutional method for effectively restructuring dimensions of different feature groups. Modifying the feature structure enhances correlations between different groups. Additionally, we introduce the MSC-Shuffle block to facilitate information flow between different feature groups. Unlike traditional Shuffle operations that focus solely on channel correlation, the MSC-Shuffle block proposed in this paper enables information exchange between different groups in both channel and spatial dimensions, thereby achieving superior segmentation performance. Experimental evaluations on two cardiac ultrasound image datasets and one chest CT image dataset demonstrate that RGShuffleNet achieves performance superior to various other state-of-the-art methods while maintaining lower complexity. Finally, RGShuffleNet is deployed on portable devices. The source code of the project is available at https://github.com/Zemin-Cai/RGShuffleNet.

  • Research Article
  • 10.3233/jifs-179611
The finite element analysis of the influence of the load change of the internal oblique muscle on the near end of the patellar tendon based on the three-dimensional image model of MRI
  • Apr 30, 2020
  • Journal of Intelligent & Fuzzy Systems
  • Na Liu

Medical image segmentation is an important step of medical image processing, which divides medical image into thousands of regions and extracts the regions of tissues and organs of interest. The accuracy of segmentation is very important for the follow-up processing of medical image and doctors’ judgment of the real situation of diseases. Medical image segmentation is a classic problem in the field of image segmentation. 3D image reconstruction technology is to obtain 3D structure information from 2D images of objects, to provide users with realistic 3D graphics, and to restore the prototype of objects, so that users can observe and analyze from multiple perspectives, which greatly improves the accuracy of measurement and the scientific accuracy of medical diagnosis, and plays a very important role in assisting doctors in clinical diagnosis. Based on the three-dimensional image model of MRI, the load variation of the internal oblique muscle can be applied to the finite element analysis of the near end of the patellar tendon.

  • Research Article
  • Cite Count Icon 29
  • 10.1016/j.compbiomed.2023.107627
LGI Net: Enhancing local-global information interaction for medical image segmentation
  • Oct 25, 2023
  • Computers in biology and medicine
  • Linjie Liu + 4 more

LGI Net: Enhancing local-global information interaction for medical image segmentation

  • Research Article
  • Cite Count Icon 15
  • 10.1016/j.cmpb.2024.108278
URCA: Uncertainty-based region clipping algorithm for semi-supervised medical image segmentation
  • Jun 11, 2024
  • Computer Methods and Programs in Biomedicine
  • Chendong Qin + 2 more

URCA: Uncertainty-based region clipping algorithm for semi-supervised medical image segmentation

  • Research Article
  • Cite Count Icon 34
  • 10.1016/j.bspc.2019.101589
Medical image segmentation algorithm based on feedback mechanism convolutional neural network
  • Jun 18, 2019
  • Biomedical Signal Processing and Control
  • An Feng-Ping + 1 more

Medical image segmentation algorithm based on feedback mechanism convolutional neural network

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