Abstract
To study 1.06μm laser causing pain in human skin. The skin of human dorsum hand was irradiated by a Nd: YAG laser. The energy of each pulse and whether the subjects felt a painful sensation after each stimulus were recorded. The pain threshold was defined as the laser dose at which the subjects reported a painful sensation to 50% of stimulus deliveries. The pain thresholds were determined under 3 different beam diameter and pulse duration conditions. The influence of skin temperature on the pain caused by laser stimulus was also explored. As the temperature of skin was about 30°C, the pain thresholds were 394mJ/mm<sup>2</sup>, 36.4mJ/mm<sup>2</sup> and 8.92mJ/mm<sup>2</sup> respectively under the stimulating condition of 1.20mm beam diameter and 85μs pulse duration, 1.20mm beam diameter and 20ns pulse duration and 2.56mm beam diameter and 20ns pulse duration. Under the first condition, when skin temperature was 25°C and radiant exposure was 383mJ/mm<sup>2</sup>, the probability of laser stimulus causing pain was 16.7%; when skin temperature was 39°C and radiant exposure was 361mJ/mm<sup>2</sup>, the probability was 56.7%. The threshold of 1.06μm laser stimulus causing pain decreases with decreasing pulse duration, increasing beam diameter and skin temperature.
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