Abstract

<strong>Background:</strong> Hemiballism/hemichorea commonly occurs as a result of a lesion in the subthalamic region. <strong>Case Report:</strong> A 38-year-old male with Parkinson’s disease developed intractable hemiballism in his left extremities due to a small lesion that was located adjacent to the right deep brain stimulation (DBS) lead, 10 months after bilateral subthalamic nucleus (STN)-DBS placement. He underwent a right globus pallidus internus (GPi)-DBS lead implantation. GPi-DBS satisfactorily addressed his hemiballism. <strong>Discussion:</strong> This case offered a unique look at basal ganglia physiology in human hemiballism. GPi-DBS is a reasonable therapeutic option for the treatment of medication refractory hemiballism in the setting of Parkinson’s disease.

Highlights

  • Hemiballism is an involuntary hyperkinetic movement disorder characterized by unilateral, violent, and flinging movements of the limbs[1] and can result from a lesion in the contralateral or ipsilateral subthalamic nucleus (STN), the subthalamic region, the thalamus, and several other brain regions.[2,3,4] Hemiballism is more severe when resulting from an STN lesion than when caused by involvement of other brain regions

  • We report a unique case where deep brain stimulation (DBS) of the globus pallidus internus (GPi-DBS) was utilized to suppress hemiballism resulting from a subthalamic stroke

  • We present the details of the case and the physiological recordings from the DBS surgery

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Summary

Case Reports

Genko Oyama[1], Nicholas Maling[1], Amanda Avila-Thompson[1], Pam R.

Introduction
Case report
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