Reproduction recovery of cows with postnatal liver damage using a liver hydrolysate drug

Abstract

Assessment of the effectiveness of treatment and recovery of reproductive functions of cows with fatty liver decease using a drug based on a healthy liver hydrolysate (the enzyme structures of the protein after acid treatment and centrifugation remain in the sediment of the tissue substrate, and their released amino acids become constituent components of the over-sediment solution of the hydrolysate). Two groups of animals of 15 heads each were formed: first-calf heifers entered the first group on the first day after calving, liver pathology was indicated by an increase in its borders during percussion, and animals with clinical signs of deep fatty liver disease were included in the second group a month after calving. The dose was 40 ml daily (20 ml intramuscularly and 20 ml subcutaneously), the course of treatment was 5 days. After the 1st stage, the remaining 25 cows of both groups were considered as one experimental group of the 2nd stage, which was periodically monitored until the next calving and insemination; the control was 25 animals not subjected to hepatoprotective therapy. Cows that underwent even one treatment procedure were better adapted to the newborn period and subsequent insemination. They have faster involution of the uterus and the resumption of the sexual cycle (P <0.001), higher fertility, and a greater number of healthy calves.