Abstract
THYROID parafollicular cells contain calcitonin in a granular form. Reduction in numbers of granules and vesicles occurs during induced calcitonin secretion in vivo1, and from thyroid slices2. Particulate fractions with the biological activity of calcitonin have been derived from homogenates of pig, calf and rat thyroid glands3,4. We have prepared calcitonin containing particulate fractions from pig thyroid and have studied the properties of the isolated granules.
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