Abstract

Human papillomavirus(HPV)is a main pathogen causing epithelial papillomatosis disease like condyloma acuminatum. HPV L1 protein plays an important role in adhering host cell, recognizing virus receptor and trafficking DNA to cellular nucleus due to its structure and antigenic character, and attack great concern is in the clinical evaluations of HPV infectivity and the researches of HPV vac cines. In the article, the structure and function of HPV L1 protein and its application are reviewed. Key words: Papillomaviridae; Capsid proteins; Condyloma acuminatum

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