Abstract

To study the relationship of nonsyndromic cleft lip and/or palate (NSCL/P) and poliovirus receptor-related 1 exon3 (PVRL1exon3) polymorphisms in Han People of Jiangzhe area. PVRL1exon3 was examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique in the 50 patients with NSCL/P and 85 healthy parents. No W185X mutation was found in the PVRL1exon 3. It indicates that there is no relationship between NSCL/P and PVRL1exon3 in Han People in Jiangzhe area.

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