Abstract
Aim: To examine the association between individual components of metabolic syndrome (MetS) and bone mineral density (BMD) among postmenopausal women. Methods: A total of 177 postmenopausal women participated in a cross-sectional study. They were interviewed to collect anthropometric and demographic characteristics. BMD was measured and biochemical parameters were estimated in fasting blood samples. Univariate and multivariate analyses were used to examine the association between individual components of MetS and BMD. Results: Among 177 postmenopausal women, 116 (66%) had MetS. Women with MetS had significantly higher mean values of BMD and T scores at the total hip (P Conclusions: Body weight and osteocalcin were more strongly associated with bone mass than any other component of MetS in postmenopausal women. However, further studies seem to be needed to confirm their observation.
Highlights
Metabolic syndrome (MetS) is defined by a cluster of cardiovascular risk factors that are associated with an increased risk of diabetes mellitus [1]
Serum TG, FBG, and insulin were significantly higher among women with MetS compared with their control counterparts (P < 0.0001)
bone mineral density (BMD) at any site was inversely correlated with serum osteocalcin levels among postmenopausal women with MetS (Figures 2(a)-(c))
Summary
Metabolic syndrome (MetS) is defined by a cluster of cardiovascular risk factors that are associated with an increased risk of diabetes mellitus [1]. The association between these risk factors and the presence of osteoporosis has been reported previously, but the results of these studies are inconsistent [2]-[4]. Hyperglycemia is a predictor of bone loss and osteoporotic fractures, but the association between high blood glucose levels or insulin resistance with bone mineral density (BMD) is inconclusive [7]. Reports of associations between high triglycerides or low HDL levels with BMD are inconsistent [3]. There have been inconsistent reports on the relationship between hypertension and BMD [3]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
