Relationship between brainstem auditory function during the neonatal period and depressed Apgar score

Abstract

Objective. To understand whether infants with depressed Apgar scores are at high risk of brainstem auditory impairment, we examined the relationship between brainstem auditory function during the neonatal period and depressed Apgar score.Methods. Brainstem auditory evoked responses (BAERs) were recorded from day 1 to day 30 in 145 term infants with Apgar scores ≤ 6.Results. For 1-min Apgar score none of BAER response wave latencies and interpeak intervals during the first 15 days correlated significantly with the score. On day 30, all wave latencies but no intervals correlated negatively with the score (all p < 0.05). For 5-min Apgar score, only on day 3 wave V latency and I–V and III–V intervals correlated negatively with the score (all p < 0.05). For 10-min Apgar score, only III–V interval correlated negatively with the score (p < 0.05). No correlation was found between BAER variables on any other days and 5 and 10-min Apgar scores. Wave V latency and I–V and III–V intervals on day 3 were all significantly longer in infants with 5-min Apgar scores ≤ 6 than in those with scores > 6.Conclusions. During the neonatal period, only on day 3 after birth a depressed 5-min Apgar score is an indicator associated with central auditory impairment. A depressed 1-min score may be associated with later peripheral auditory impairment.