Abstract
To determine if sperm morphology after capacitation affects intrauterine insemination outcomes. Retrospective cohort study between December 2018 and April 2019. A total of 166 couples with unexplained infertility and 284 cycles of ovarian stimulation for intrauterine insemination were done at the IECH Fertility Center in Monterrey, Nuevo León, México and were divided between two groups: Group 1 (study group) were patients with teratospermia (sperm morphology <4%) and Group 2 (control group) were patients with normal sperm morphology (>4%). The main variable results were pregnancy rate per cycle. Sperm count, progressive motility, total count and morphology were analyzed in spermogram. Demographic outcomes were homogeneous among two groups. Male patients between 31-35 years had major proportion of severe teratospermia. No statistical significance pregnancy rate was observed with the two groups (17 vs 23 p=0.2 OR=1.6). Cohort point to predict birth rate in this studied population was 5.5% with a specificity of 81% and sensibility of 30%. Patients with teratospermia had primary infertility with statistical significance comparable with control group (79.79% vs 68.42&, p= 0.0493, OR 1.82). Teratospermia can’t be count as a parameter to predict pregnancy in this population. Couples with unexplained infertility and sperm morphology greater that 5.5% increases chances of getting pregnant.
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