Abstract
1. 1. The synthesis of medium-chain fatty acids by cell-free extracts of rabbit and rat mammary glands in proportions similar to those synthesized in vivo only occurred at high protein concentrations. The inability of subcellular fractions of guinea-pig mammary gland to synthesize medium-chain fatty acids correlates with the presence of only long-chain fatty acids in guinea-pig milk fat. 2. 2. Dilution of subcellular fractions progressively increased the proportion of long-chain fatty acids synthesized until the pattern resembled that obtained with isolated fatty acid synthetase. 3. 3. The specificity of fatty acid synthesis was not influenced by the esterification of the synthesized fatty acids into glycerides. 4. 4. Fatty acid synthetase may interact with other protein components in the particle-free supernatant fraction of rabbit and rat mammary gland, thereby altering its chain-length specificity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Comparative Biochemistry and Physiology -- Part B: Biochemistry and Molecular Biology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
