Regression of primary lymphoma of the ampulla of Vater after eradication of Helicobacter pylori

Abstract

Primary lymphoma of the major duodenal papilla is extremely rare. 1 Ventrucci M Gherlinzoni F Sabattini E Cipolla A Ubalducci GM Pileri S Primary MALT-lymphoma of the papilla of Vater. Dig Dis Sci. 1998; 43: 214-216 Crossref PubMed Scopus (17) Google Scholar , 2 Pawade J Lee CS Ellis DW Vellar ID Rode J Primary lymphoma of the ampulla of Vater. Cancer. 1994; 73: 2083-2086 Crossref PubMed Scopus (32) Google Scholar , 3 Zhu L Slee GR Domenico DR Mao C Howard JM B-cell lymphoma of ampulla of Vater: observation for six years. Pancreas. 1995; 10: 208-210 Crossref PubMed Scopus (9) Google Scholar , 4 Misdraji J Fernandez del Castillo C Ferry JA Follicle center lymphoma of the ampulla of Vater presenting with jaundice: report of a case. Am J Surg Pathol. 1997; 21: 484-488 Crossref PubMed Scopus (61) Google Scholar , 5 Barek L Orron D Non-Hodgkin's lymphoma presenting as periampullary mass with obstructive jaundice. J Comput Tomogr. 1986; 10: 89-92 Abstract Full Text PDF PubMed Scopus (18) Google Scholar , 6 Kelly SB Price P Williamson RC Non-Hodgkin's lymphoma presenting with jaundice and hypercalcaemia. Clin Oncol (R Coil Radiol). 1993; 5: 122-123 Abstract Full Text PDF PubMed Scopus (7) Google Scholar , 7 Schoeppner HL Wong DK Bresalier RS Primary small bowel lymphoma manifested as obstructive jaundice in a patient with AIDS. South Med J. 1995; 88: 583-585 Crossref PubMed Scopus (10) Google Scholar , 8 Swartz TR Ritchie WG Bile duct obstruction secondary to lymphomatous involvement of the pancreas. J Clin Ultrasound. 1983; 11: 391-394 Crossref PubMed Scopus (14) Google Scholar , 9 Young IF Roberts-Thomson IC Sullivan JR Histiocytic lymphoma presenting with extrahepatic biliary obstruction: a report of three cases. Aust N Z J Surg. 1981; 51: 181-183 Crossref PubMed Scopus (28) Google Scholar , 10 Yoshino T Miyake K Ichimura K Mannami T Ohara N Hamazaki S et al. Increased incidence of follicular lymphoma in the duodenum. Am J Surg Pathol. 2000; 24: 688-693 Crossref PubMed Scopus (196) Google Scholar Patients with lymphoma involving this structure have been treated by pancreatoduodenectomy, radiotherapy, or chemotherapy. Lymphoma of the mucosa-associated lymphoid tissue (MALT), now classified as extranodal marginal zone B-cell lymphoma of MALT type in the World Health Organization (WHO) classification of hematologic malignancies, 11 Harris NL Jaffe ES Diebold J Flandrin G Muller-Hermelink HK Vardiman J et al. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997. J Olin Oncol. 1999; 17: 3835-3849 PubMed Google Scholar are most frequently located in the GI tract. More than 90% of gastric MALT lymphomas are diagnosed in patients with chronic Helicobacter pylori-associated gastritis. High remission rates for these lymphomas have been observed after eradication of H pylori infection. 12 Wotherspoon AC Doglioni C Diss TC Pan L Moschini A de Boni M et al. Regression of primary low-grade B-cell gastric lymphoma of mucosa associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet. 1993; 342: 575-577 Abstract PubMed Scopus (1994) Google Scholar , 13 Nakamura T Nakamura S Yonezumi M Suzuki T Matsuura A Yatabe Y et al. Helicobacter pylori and the t(11;18)(q21;q21) translocation in gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type. Jpn J Cancer Res. 2000; 91: 301-309 Crossref PubMed Scopus (69) Google Scholar However, little is known about lymphoma arising in the duodenum because it is so rare. The relationships between H pylori infection, duodenal lymphoma, and the possible therapeutic efficacy of H pylori eradication are controversial. 1 Ventrucci M Gherlinzoni F Sabattini E Cipolla A Ubalducci GM Pileri S Primary MALT-lymphoma of the papilla of Vater. Dig Dis Sci. 1998; 43: 214-216 Crossref PubMed Scopus (17) Google Scholar , 14 Nagashima R Takeda H Maeda K Ohno S Takahashi T Regression of duodenal mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori. Gastroenterology. 1996; 111: 1674-1678 Abstract Full Text PDF PubMed Scopus (94) Google Scholar , 15 Kim JS Jung HC Shin KH Song IS Kim CW Kim CY Eradication of Helicobacter pylori infection did not lead to cure of duodenal mucosa-associated lymphoid tissue lymphoma. Scand J Gastroenterol. 1999; 34: 215-218 PubMed Google Scholar