Abstract
The study aimed to verify histologically the bone repair following the use of resorbable collagen membrane with or without ethyl cyanoacrylate fixation. A 2mm bone defect in the femur of 24 Wistar rats was made. In group I, the bone wound was covered by a resorbable membrane without fixing; in group II, the membrane was fixed using ethyl cyanoacrylate. At 15 days, group I had bone defects filled with irregular interconnecting trabecular bone. The group II showed irregular bone spicules, with intense inflammatory infiltrate. At 30 days, in group I, there was a lamellar bone tissue formation, while in Group II, there was irregular trabecular bone and persistence of inflammatory infiltrate. It was conclude that the use of ethyl cyanoacrylate intensified inflammatory reaction, slowing bone healing.
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