Abstract

Systemic Mastocytosis (SM) can be associated with Acute Myeloid Leukemia (AML) and mast cells can be masked on bone marrow biopsy by the high burden of blast cells. Most of the SM-AML patients have associated translocation t(8;21) and mutation of D816V KIT gene which were not present in the reported case. None of the SM-AML cases described in the literature had systemic symptoms secondary to SM. This is the first reported case of life-threatening symptomatic SM in a patient with SM-AML. Checking

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