Abstract
Drug Life Cycle Management (LCM) includes a variety of strategies that are implemented by biotech and pharmaceutical companies to uncover the hidden value of the drug and maximize their sales and extend their commercial lives. Drug reformulation is one of the most widely used line extension strategies, which expands the therapeutic utility of drugs in different ways and provides market exclusivity. Reformulation allows pharmaceutical companies to address specific marketing needs, helps in strengthening a brand, repositioning a drug in an entirely new target population or even new therapeutic area or effectively treat patients with a specific clinical need. The motivation for a company to reformulate its brand varies according to when the reformulation is implemented during the life cycle of the drug. In this review, we present and discuss the life cycle of two new molecular entities approved by the US Food and Drug Administration during the 2001-2010 decade, aripiprazole (Trade name, Abilify) and lacosamide (Trade name, Vimpat), highlighting the reformulation strategies adopted.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
