Abstract
A broadband adaptive optics scanning ophthalmoscope (BAOSO) consisting of four afocal telescopes, formed by pairs of off-axis spherical mirrors in a non-planar arrangement, is presented. The non-planar folding of the telescopes is used to simultaneously reduce pupil and image plane astigmatism. The former improves the adaptive optics performance by reducing the root-mean-square (RMS) of the wavefront and the beam wandering due to optical scanning. The latter provides diffraction limited performance over a 3 diopter (D) vergence range. This vergence range allows for the use of any broadband light source(s) in the 450-850 nm wavelength range to simultaneously image any combination of retinal layers. Imaging modalities that could benefit from such a large vergence range are optical coherence tomography (OCT), multi- and hyper-spectral imaging, single- and multi-photon fluorescence. The benefits of the non-planar telescopes in the BAOSO are illustrated by resolving the human foveal photoreceptor mosaic in reflectance using two different superluminescent diodes with 680 and 796 nm peak wavelengths, reaching the eye with a vergence of 0.76 D relative to each other.
Highlights
Ophthalmic adaptive optics (AO) instruments allow in vivo visualization of microscopic retinal features by compensating for the monochromatic aberrations of the eye [1]
Most scanning ophthalmic AO instruments use one or more afocal telescopes formed by pairs of spherical mirrors used in planar off-axis arrangements that are dominated by astigmatism
A broadband adaptive optics scanning ophthalmoscope consisting of four reflective afocal telescopes was presented
Summary
Ophthalmic adaptive optics (AO) instruments allow in vivo visualization of microscopic retinal features by compensating for the monochromatic aberrations of the eye [1]. Gómez-Vieyra et al [13] showed that by folding these reflective telescopes in a non-planar configuration, it is possible to completely cancel the astigmatism at one point in the field of view (FOV) either in the pupil or image conjugate planes.
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