Abstract

Introduction. Chronic thromboembolic pulmonary hypertension (CTEPH) represents uncommon or under-diagnosed sequel of acute or chronic pulmonary embolism (PE). The gold standard therapy for CTEPH is pulmonary endarterectomy (PEA) which markedly improves the prognosis or even cures the disease in the majority of patients with CTEPH [1]. Nevertheless some CTEPH patients are not operable due to small-vessel disease (“distal CTEPH”) due to significant co-morbidities making the risk of surgery unacceptably high [2,3].

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