Abstract
Addressing the multifaceted aspects of asthma care calls for a thorough examination of new evidence regarding additional effects of treatments, as well as pioneering a paradigm shift in treatment outcomes. The concept of “people remodeling” unveils the complex interplay between changes in body weight and the use of oral corticosteroids, particularly highlighting how obesity, often a consequence of medication side effects, significantly influences asthma management. Simultaneously, integrating exercise into asthma treatment has undergone a transformative evolution, shifting from careful consideration to a pivotal cornerstone. Within the landscape of severe asthma treatment, the introduction of biological therapies has triggered a profound revolution by presenting the possibility of achieving clinical/complete remission, representing a departure from the conventional control goal. This review will discuss recent articles focusing on weight loss associated with biologics in patients with severe asthma, the effects of exercise on lung function in asthmatics and a consensus definition of clinical remission in severe asthma.
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