Abstract
Abstract This chapter presents the case of a young woman who suffers from red burning feet since the age of 1 year, triggered by warmth and relieved by cooling. Clinical examination shows no sensory impairment, tendon reflexes are normal, and there is no motor deficit, but there is clear erythema of the feet. Pain is poorly relieved by codeine and acetaminophen. Erythromelalgia is a rare condition characterized by episodic burning pain and erythema of the distal extremities, aggravated by warmth and exercise. The diagnosis is clinical. Primary erythromelalgia is genetic, and oral mexiletine or topical lidocaine may be helpful. Secondary causes include myeloproliferative diseases, autoimmune disorders, small fiber neuropathy, vasodilated drugs, and collagen disorders/joint hypermobility.
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