Abstract
Haemangiopericytoma (HPC) is a rare soft-tissue tumour with great histological variability and unpredictable clinical and biological behaviour. HPC of the bladder is exceedingly rare and carries uncertain malignant potential. The current study reports a case of HPC of the bladder in a 48-year-old female, who was admitted to the Sir Run Run Shaw Hospital (Hangzhou, China) due to a large bladder mass. The patient exhibited no mass-related symptoms, such as pain, gross haematuria or urinary irritation. Seven years prior to admission, the patient underwent surgical resection of a bladder mass, which was determined to be HPC. Computed tomography scans showed a well-defined, heterogeneously enhancing solid cystic mass in the bladder. The patient underwent complete excision of the tumour and a partial cystectomy. The histopathological diagnosis was HPC of the bladder. The post-operative recovery was uneventful and no evidence of recurrence or metastasis was identified during two years of follow-up. The clinical and histological features, and the treatment and prognosis of this tumour are discussed together in the present study, with a review of the literature.
Highlights
The majority of primary bladder tumours are transitional cell tumours
Haemangiopericytoma (HPC) of the bladder, which is a tumour originating from the vascular pericytes of Zimmermann, is exceedingly rare and carries uncertain malignant potential
The current study reports a case of recurrent primary HPC of the bladder
Summary
The majority of primary bladder tumours are transitional cell (urothelial) tumours. Haemangiopericytoma (HPC) of the bladder, which is a tumour originating from the vascular pericytes of Zimmermann, is exceedingly rare and carries uncertain malignant potential. A 48‐year‐old female patient was admitted to the Sir Run Run Shaw Hospital (Hangzhou, China) due to a large mass in the bladder identified during a health examination in June 2011. Seven years prior to admission, the patient underwent surgical resection of a bladder mass, which was diagnosed as HPC of the bladder. The histopathological examination revealed a neoplasm consisting of spindle‐shaped cells, which were arranged around the vasculature, with a ‘staghorn’ configuration (Fig. 2). The images captured were hypercellular and showed cells that exhibited oval nuclei. The histopathological diagnosis was HPC of the bladder and surgical margins were noted to be tumour‐negative.
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