Abstract
BackgroundOculomotor nerve palsy (ONP) is a common clinical presentation of posterior communicating artery (PcomA) aneurysms. It remains unclear if patients have a better rate of recovery after surgical clipping or endovascular coiling.ObjectivesThe main objectives of this study were to assess the overall rate of ONP recovery after endovascular coiling of PcomA aneurysms, as well as to determine the associated predictive factors of oculomotor nerve recovery.MethodWe retrospectively evaluated the demographic, clinical, and radiological characteristics and the outcome of consecutive patients presenting with PcomA aneurysms treated by endovascular coiling from January 2012 to November 2016 with at least 1 year clinical and radiological follow-up. Statistical analysis was applied to determine the association between ONP recovery and the demographic, clinical and radiological variables.ResultsA total of 91 patients with PcomA aneurysms were treated endovascularly. Thirty-four patients (22 women and 12 men) with ONP related to PcomA aneurysms were included. The mean age of the patients was 49.8 years. Subarachnoid haemorrhage was present in 27 patients. The mean aneurysm size was 6.7 mm. The overall rate of recovery was 88.2%. Complete nerve recovery was seen in 16 (47%) patients and partial recovery was observed in 14 (41.2%) patients, whilst 4 (11.8%) patients remained unchanged after treatment. The non-posterolateral direction of the aneurysm showed a tendency towards better recovery compared to the posterolateral projection (p = 0.06).ConclusionEndovascular coiling of PcomA aneurysms in patients with ONP resulted in a cure or improvement of oculomotor nerve dysfunction in the majority of patients.
Highlights
Posterior communicating artery (PcomA) aneurysms are one of the most common aneurysms encountered by neurosurgeons and neuro-interventional radiologists, representing 50% of all internal carotid artery (ICA) aneurysms
The study population consisted of 91 patients who each presented with a PcomA aneurysm
We found that 43.9% of patients with PcomA aneurysms developed Oculomotor nerve palsy (ONP)
Summary
Posterior communicating artery (PcomA) aneurysms are one of the most common aneurysms encountered by neurosurgeons and neuro-interventional radiologists, representing 50% of all internal carotid artery (ICA) aneurysms. They are the second most common aneurysms overall (25% of all aneurysms).[1] Oculomotor nerve palsy (ONP) is a common clinical presentation of both ruptured and unruptured PcomA aneurysms and has been reported to vary from 35% to 45%.2,3. Oculomotor nerve palsy (ONP) is a common clinical presentation of posterior communicating artery (PcomA) aneurysms It remains unclear if patients have a better rate of recovery after surgical clipping or endovascular coiling
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
