Recombination: Implications of Single Nucleotide Polymorphisms for Plant Breeding

Abstract

Single-nucleotide polymorphisms (SNPs) are the most abundant type of DNA sequence variation in humans, animals and plants (Landegren et al. 1998; Schafer and Hawkins 1998; Wang et al. 1998; Gilles et al. 1999; See et al. 2002). SNPs, which are in the narrow sense single-base substitutions (transitions or transversions) in a DNA sequence, as well as small insertions and deletions (InDels) represent the most promising markers for plant breeding, so far. Although SNPs are biallelic, large numbers can be combined to form haplotypes making SNPs highly informative in comparison to other types of molecular markers such as RFLPs or SSRs (Meyer et al. 2000; Rafalski 2002a). Recent advances in SNP technologies, especially in the field of high-throughput applications (Gupta et al. 2001, Jander et al. 2002), allow SNP scoring and screening in plants on a large scale or even genome-wide (Buckler and Thornsberry 2002; Rafalski 2002a,b; Cho et al. 1999).KeywordsLinkage DisequilibriumAssociation MappingMaize Inbred LineSoybean Cyst NematodeSugarcane Mosaic VirusThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.