Abstract
It has been demonstrated that the use of GnRH analogues decreases the concentration of LH available to developing follicles, nevertheless, both gonadotrophins, LH and FSH, are crucial to normal follicular development. Luteinizing hormone also plays an important role in oocyte maturation during natural cycles. However, whether patients undergoing COS may benefit from co-administration of r-LH and r-FSH, when either a GnRH-antagonist or a GnRH-agonist protocol is used is to be elucidated. The goal for the present study was to evaluate the effect of the combination of recombinant LH (rLH) with recombinant FSH (rFSH) on ICSI clinical outcomes.
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