Abstract
Diagnosis and Treatment1 November 1967Recognition of Digitalis Intoxication in the Presence of Atrial FibrillationJOHN A. KASTOR, M.D., PETER M. YURCHAK, M.D., F.A.C.P.JOHN A. KASTOR, M.D.Search for more papers by this author, PETER M. YURCHAK, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-5-1045 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere is no agent in the pharmacopeia so useful, yet so potentially hazardous, as digitalis. Lifesaving to thousands with heart failure, it has been life-ending to countless others in whom signs of toxicity went unrecognized.PREDISPOSING FACTORSPhysicians have become increasingly aware in recent years of the symptoms and electrocardiographic signs of digitalis intoxication. This is due in part to detailed descriptions of certain characteristic digitalis-induced arrhythmias (1). Furthermore, there is growing recognition that the toxic dose is often not far removed from the therapeutic (2-4) and that certain patients are predisposed to the development of toxic manifestations. Some of...
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