Abstract

Anti-motion sickness, especially the seasickness, as one of the most common seen symptoms in long-term journey, can affect the normal work and life of crew members seriously. The purpose of this study is to investigate the anti-seasickness, anti-fatigue and functional constipation improving effects of anti-motion sickness biscuits in mouse model. Behavioral experiments together with biochemical indicators of mice were investigated under different doses of compressed biscuits. Results of the study indicate that mice fed with compressed biscuits containing medium and high doses of the anti-motion sickness ingredient can significantly improve the learning, memory and swimming ability compared to the control group. Furthermore, glycogen, LA and LDH levels of the mice can be increased with decreased BUN and Passe levels under the treatment of anti-motion sickness compressed biscuits. The results suggest that the compressed biscuits have anti-seasickness and anti-fatigue effects. In addition, the impact of pear residue in the compressed biscuits on the functional constipation of mice was also discussed in this paper.

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