Abstract

Fluorescence-activated cell sorting (FACS), a cell isolation approach that relies on immunofluorescent signals, is among the most frequently applied approaches. Due to the inherent advantages of microfluidic devices in terms of small size, short detection time and low cost, their application in biotechnology are currently being investigated. Current research by scholars was reviewed by the literature method. Micro-magnet matrices can be used to move multiple cells in cell manipulation, and open tubular with magnetic trapping bead trap beds can be useful in trapping blood cells. The trapping and separation of blood cells have been better progressed, and future studies can concentrate on the concurrent sorting of several targets at high purity, recovery, and throughput levels, label-free continuous separation of cell mixtures, and the sorting of different cells by changing the device environment around the properties of the magnetic device itself.

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