Abstract

A year ago, film-based fluorescent sensors (FFSs) were recognized in the "IUPAC Top Ten Emerging Technologies in Chemistry 2022" due to their extensive application in detecting hidden explosives, illicit drugs, and volatile organic compounds. These sensors offer high sensitivity, specificity, immunity to light scattering, and noninvasiveness. The core of FFSs is the construction of high-performance fluorescent sensing films, which are dependent on the processes of "energy transfer" and "mass transfer" in the active layer and involve complex interactions between sensing molecules and analytes. This Perspective focuses on the latest strategies in constructing these films, emphasizing the design of sensing molecules with various innovative features and structures that enhance the mass transfer efficiency. Additionally, it discusses the ongoing challenges and potential advancements in the field of FFSs.

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