Reassessing cholecystectomy timing in gallstone-related acute cholangitis.

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In this article, we discussed the article by Sohail et al, published in a recent issue of the World Journal of Gastrointestinal Endoscopy. This study highlights the benefits of performing cholecystectomy (CCY) during the same hospitalization for patients with acute cholangitis (AC) associated with gallstones. Specifically, same-admission CCY is associated with significantly lower 30-day readmission rates compared with interval CCY. Furthermore, it has been associated with reduced mortality rates and reduced recurrence of biliary symptoms. Despite these advantages, the procedure is chosen in only a minority of eligible patients. This gap between evidence and practice highlights the need for updated clinical guidelines and further research to optimize the timing of CCY in the management of AC.