Abstract
The effects of long-term oral administration of nicotine (N; 0.01%) on the rearing response and the complex T-maze learning of WKY rats were investigated. N slightly increased the locomotion, and increased the rearing response more than the control (C) rats in the night. During daily 6-trial T-maze learning for 4 days, N enhanced the learning in both the number of errors and the latency measures. Scopolamine (40mg/kg) administered on the 5th session reduced the T-maze performance in the C rats, but not in the N animals.
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