Abstract
Background: The rapid development of multiple myeloma (MM) management underscores the value of real-world data. In our studywe examined 509 adult MM patients treated with immunochemotherapy (ICT) with/without stem cell transplantation (SCT) from2013 to2019 in the Hospital District of Helsinki and Uusimaa, Finland. Materials & methods: Ourstudy was based on computational analyses of data integrated into the hospital data lake. Results: After2017, treatment pattern diversity increased with improved access to novel treatments. 5-year survivals were 74.4% (95% CI: 65.5-84.5) in SCT-eligible and 44.0% (95% CI: 37.6-51.4) in non-SCT subgroups. In the SCT-eligible subgroup, high first-year hospitalization costs were followed by stable resource requirements. Conclusion: Hospital data lakes can be adapted to carry outcomplex analysis of large MM cohorts.
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