Abstract
Kinetic isotope effects reveal mechanistic insight into chemical reactions. Larger isotope ratios often lead to larger changes in rate, and, commonly, the largest ratio is 2—for the substitution of deuterium for hydrogen. Fleming et al. (p. [448][1]; see the Perspective by [Alexander][2] ) compared results for the simplest chemical reaction, of an H atom with H2, for two hydrogen isotopes created with positive and negative muons, which provide an unprecedentedly large mass ratio of 36. At 500 kelvin, the relative reaction rates measured agreed with those calculated using variational transition state theory. [1]: /lookup/doi/10.1126/science.1199421 [2]: /lookup/doi/10.1126/science.1201509
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
