Abstract

IntroductionThe safety of dipyrone has been the subject of several debates; severe allergic reaction can occur; its incidence is 1 in 5.000 parenteral administrations. Clinical findingsA case of a patient who following an infusion with dipyrone has a cough, pharyngeal pruritus, dyspnea, cyanosis and generalized impairment of consciousness. The diagnosis of anaphylactic shock by dipyrone in a patient without hypersensitivity precedent is reported, despite treatment with endotracheal intubation, adrenaline, hydrocortisone, sodium chloride and sodium bicarbonate, which proved fatal. ConclusionSerious cases of hypersensitivity may occur in patients with no history of it; it is important recognized this risk in our patients.

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