Abstract
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center for the global PDB archive, serves thousands of Data Depositors in the Americas and Oceania and makes 3D macromolecular structure data available at no charge and without usage restrictions to more than 1 million rcsb.org Users worldwide and 600 000 pdb101.rcsb.org education-focused Users around the globe. PDB Data Depositors include structural biologists using macromolecular crystallography, nuclear magnetic resonance spectroscopy and 3D electron microscopy. PDB Data Consumers include researchers, educators and students studying Fundamental Biology, Biomedicine, Biotechnology and Energy. Recent reorganization of RCSB PDB activities into four integrated, interdependent services is described in detail, together with tools and resources added over the past 2 years to RCSB PDB web portals in support of a ‘Structural View of Biology.’
Highlights
The field of structural biology has been transformed by frequent advances in technology for every aspect of the structure determination pipeline since the Protein Data Bank (PDB) was established in 1971 [1] as the first open-access digital data resource in biology [2,3,4,5,6]
RCSB PDB Archive Management/Access and Data Exploration Services provide a one-stop shop for >1 million rcsb.org users annually, who want to understand any one of >145 000 PDB structures in the context of pre-organized scientific information drawn from ∼40 external biodata resources
In 2014, the inaugural RCSB PDB Berman et al [3] article was ranked 92nd in the top 100 all time cited publications by the Web of Science [44], providing a useful data set for bibliometric analyses
Summary
The field of structural biology has been transformed by frequent advances in technology for every aspect of the structure determination pipeline since the Protein Data Bank (PDB) was established in 1971 [1] as the first open-access digital data resource in biology [2,3,4,5,6]. Since our last Nucleic Acids Research Database Issue publication [8], RCSB PDB activities have been reorganized into four integrated, interdependent cyberinfrastructures services, RCSB PDB hardware and software have been upgraded and new tools and resources have been introduced.
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