Abstract
The main reason for the application of heavy ions like carbon in radiotherapy is the enhanced relative biological effectiveness RBE. In contrast to neutrons where RBE is widely independent from penetration depth, high energy carbon beams have a low RBE at the entrance and a high RBE in the target-volume. Therefore, the side effects to normal tissue are small, while the tumor response can be maximized. In the paper, experimental RBE values for inactivation are compiled, that demonstrate the RBE dependence from the repair capacity. In a theoretical approach, the local effect model (LEM), this dependence is used to calculate clinical RBE. Examples for clinical RBEs are given that have been applied to patient treatments.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
