Abstract
-A new set of RBE and OER measurements are reported for ten neutron energies between 60 ke V and 15 Me V obtained at the Radiological Research Accelerator Facility at Brookhaven National Laboratory. In addition two higher energy neutron beams were studied at the Naval Research Laboratory in Washington and at the Texas A&M Cyclotron. Two biological test systems were used, namely growth inhibition of Vicia seedlings and hamster cells cultured in vitro. In the case of the OER, a minimum value of 1.3 was observed for neutron energies of 220–440 keV. OER increased with neutron energy to a maximum of 1.8 for 15 McV neutrons. A slightly lower value of 1.6 was found to apply to both of the high energy cyclotron-produced neutron beams currently being introduced for radiotherapy. The plot of RBE as a function of neutron energy has a similar shape for both biological test systems employed; the maximum RBE occurs at a neutron energy of about 350 keV. The experimental data are consistent with the theoretical predictions made on the basis of microdosimelric measurements.
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