Abstract
Multiple primary neoplasms with synchronous or metachronous presentation are rare, although the incidence has recently increased because of several factors. We present the case of a 53-year-old patient with chronic hepatitis B who presented with abdominal mass, mild abdominal pain, and inguinal hernia. Computed tomography imaging demonstrated diffuse thickening of the gastric antral wall, together with a huge heterogeneous abdominal mass with predominant fat attenuation with septa that showed mild enhancement on contrast-enhanced scans. Distal gastrectomy and wide resection of the retroperitoneal mass was performed. Pathology exam led to a diagnosis of diffuse large B-cell gastric lymphoma with retroperitoneal liposarcoma. This is a rare case of a primary gastric lymphoma with another primary (sarcomatous) malignancy occurring synchronously in same patient.
Highlights
Synchronous occurrence of two primary malignancies presenting as lymphoma and sarcoma is rare, a few cases of secondary malignancy presenting in that fashion have been reported after treatment or in immunosuppression 1,2
Multiple primary neoplasms constitute approximately 2%–10% of all carcinoma cases reported in the literature
Various factors have been considered for the pathogenesis of multiple primary cancers at anatomically distinct sites
Summary
Synchronous occurrence of two primary malignancies presenting as lymphoma and sarcoma is rare, a few cases of secondary malignancy presenting in that fashion have been reported after treatment or in immunosuppression 1,2. The case described here is the first to be reported of synchronous occurrence of primary gastric lymphoma and retroperitoneal liposarcoma in an immunocompetent patient
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
