Abstract
Rapid enlargement of mediastinal nonseminomatous germ cell tumor (mediastinal NSGCT) with a fall in tumor marker levels was noted in a 43-year-old man. The patient was treated with chemotherapy (bleomycin, etoposide and cisplatin, BEP) to downsize the tumor preoperatively. The mediastinal NSGCT, however, increased in size aggressively despite decline in tumor markers, provoking critical respiratory failure that resulted in the patient's death. We describe computed tomography (CT) findings of a case of enlarging mediastinal NSGCT due to postchemotherapeutic tumor necrosis that progressed rapidly before initiation of subsequent regression.
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