Abstract
Swift and convenient handling of discrete micro-droplets on digital microfluidics platform has recently attracted plentiful interest in high-throughput bio/chemical analysis. In this work, we developed a novel and facile approach to manipulate the micro-droplet based on a hydrophobic and low-adhesive magnetically functionalized polydimethylsiloxane (MF-PDMS) membrane. The platform is composed of the MF-PDMS membrane as the substrate, integrated with non-magnetic PDMS micro-pillar arrays on-top to ensure the low adhesion between the platform and the resident drops. With applied magnetic field, the localized membrane deformation could induce the unbalanced force imposed on the micro-droplet, leading to free rolling-off for flexible control including the position and velocity, etc. We have experimentally verified that the proposed avenue could be successfully applied for kinds of on-chip micro-droplet manipulations, such as droplet merging, parallel manipulation, flexible trajectory control. With the flexibility and maximum velocity reported herein (~ 79 ± 6 mm/s), we believe that the presented platform could be potentially applied for biological or chemical analysis where precise manipulation of large amounts of individual droplets is critical.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
